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Remembering Bonnie Kaye

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A memorial and celebration of life for Bonnie Kaye will take place on Sunday, Feb. 26, at 2 p.m. at People Acting To Help (PATH), 1919 Cottman Ave. (at Castor Avenue), and on Zoom. Kaye died on Feb. 10 from complications of a heart catheterization. She was co-owner and director of the Northeast Learning Center, which prides itself on being No. 1 in the state in passage of the High School Equivalency Test (HiSET). ••

Book discussion series

The Northeast Regional Library Friends’ Group’s book discussion series will take place on Friday, February 24, at 2 p.m., with Dreamers, by Yuyi Morales. The book can be borrowed from Northeast Regional’s children’s department. Adults, including senior citizens and their caregivers, are encouraged to participate. Participants are welcome to bring family history items for show and tell. Northeast Regional Library is at 2228 Cottman Ave. Call 215-685-0522. ••

Experience Lenten Joy

Mother Boniface Spirituality Center (3501 Solly Ave.) will sponsor a morning of reflection, Lenten Joy, on Wednesday, March 1. Sister Mary Kay McDonald, MSBT, will invite participants to discover how the Holy Spirit’s gift of Joy can lead people on a path of conversion and prepare them for the celebration of Holy Week and Easter. The program runs from 9 a.m. to 1 p.m. It includes a breakfast snack, reflection, prayer, storytelling and lunch. The fee is $35. Visit www.msbt.org/events/lenten-joy or call 267-350-1830. ••

Learn about Joseph Zarelli

The Northeast Philadelphia History Network will meet on Wednesday, March 1, at 7 p.m. at Pennepack Baptist Meetinghouse, 8732 Krewstown Road. The topic will be The Boy in the Box & the Vidocq Society. The speaker will be William Fleisher, Vidocq co-founder. Fleisher, a former Philadelphia police officer and FBI agent, will talk on the history of the Vidocq Society and the Boy in the Box investigation, which led to the identification of Joseph Zarelli. ••

Bingo on March 11

St. Michael’s Lutheran Church, at Trenton Avenue and Cumberland Street, will hold bingo on Saturday, March 11, from 1-4 p.m. Doors open at noon. Packages are $20 and include lunch. Call 215-423-0792. ••

Bucks senior softball registration

Registration is open for the Bucks 65+ Senior Softball League. Indoor practices are held Tuesdays and Thursdays at PRAC, 375 W. Trenton Ave., Morrisville. Teams will form in April. For information, go to www.bucksseniorsoftball.com or email Bill at bbjt03@gmail.com or Jack at Zupan.jack@gmail.com. ••

Learn about Joseph and family

Joseph and His Family will be the central theme of a six-part biblical series being offered for active adults at KleinLife, 10100 Jamison Ave. The public is invited to join with members. Sessions will be conducted on Feb. 23 and March 2, 9,16, 23 and 30. All will begin at 10:30 a.m. Cost for all six sessions will be $36 per person. To register and for more information, contact Shelley Geltzer at 215-698-7300, Ext. 129 or sgeltzer@kleinlife.org. ••

Join Mamma Mia!

The Star Players are looking for some young males to join the ensemble or have small speaking roles in an upcoming production of Mamma Mia!

The show is June 2-4 at Venice Island Performing Arts Center in Manayunk. Rehearsals take place at Holmesburg Recreation Center, 4500 Rhawn St.

Any young males who want to join the show can contact director Bill Arthur at 215-685-8714 or StarPlayers2013@gmail.com. ••

Sign up for senior softball

The Philadelphia Senior Softball League is looking for experienced players for their 59-and-over and 68-and-over leagues. The seasons start mid-April and will go until the end of September. There will be about 30 games, plus playoffs. No games are played in July. The 59-and-over games are Tuesdays and Thursdays. The 68-and-over games are Mondays and Fridays. All games are played at Crispin Field, Holme and Convent avenues. Games start at 10 a.m. For more information on the 59-and-over league, call John Troy at 215-292-1437. For more information on the 68-and-over league, call Marty King at 215-409-5021. ••

St. Jerome Seniors to meet

St. Jerome’s Senior Group will meet on Thursday, Feb. 23 and March 9 and 23, in the school hall, 3031 Stamford St. Arrive by 10 a.m. Meeting begins promptly at 11 a.m. ••

Storytime at Ryerss

Ryerss Museum & Library, located at 7370 Central Ave. in Burholme Park, will host Storytime at Ryerss at 10:30 on two upcoming Saturdays. The schedule is Feb. 25 (Out of This World) and March 11 (Happy Birthday, Robert Ryerss). Call 215-685-0544. ••

Pre-Purim fun

Families are invited to join Northeast Kehillah for a pre-Purim event on Tuesday, Feb. 28, from 5:30 to 7 p.m. at KleinLife, 10100 Jamison Ave. The kid-friendly evening will feature costumes, interactive storytime, crafts, activities and a light kosher dinner. To register, go to JewishPhilly.org/NEPurim. For more information, email Carrie at northeast@kehillah.jewishphilly.org. ••

Opera shows scheduled

Amici Opera Company will present Bellini’s Bianco & Fernando on Saturday, Feb. 25, at 4 p.m. at United Methodist Church of the Redeemer, 1128 Cottman Ave.

Amici will present De Koven’s Robin Hood on Sunday, Feb. 26, at 2:30 p.m. at Dock Woods, 275 Dock Drive, Lansdale; and on Saturday, March 4, at 4 p.m. at United Methodist Church of the Redeemer.

Next up is Ponchielli’s Marion Delorme on Sunday, March 5, at 3 p.m. and Saturday, March 18, at 4 p.m. at United Methodist Church of the Redeemer.

There will be two performances of Donizetti’s La Favorita: Sunday, March 19, at 3 p.m. at United Methodist Church of the Redeemer; and Sunday, March 26, at 2:30 p.m. at Dock Woods.

Call 215-224-0257 or visit the Amici Opera Company page on Facebook. ••

Discussion on guns

WHYY and the Free Library of Philadelphia will hold a meeting, Grappling with America’s Guns, on Feb. 22, from 6 to 7:30 p.m. at Northeast Regional Library, 2228 Cottman Ave. The public is invited. ••

Family tree help

Ryerss Museum & Library, 7370 Central Ave., will host How to Dig Up Your Ancestors on Friday, March 3, at 1 p.m. The free event will help people learn how to research their family tree. The program will be led by genealogy sleuth Jane Prusso. ••

Special Shabbat

Congregations of Shaare Shamayim, 9768 Verree Road, will celebrate Shabbat Across America on Friday, March 3. Dinner will be served at 6:15 p.m., followed by services at 7:30 and concluding with an Oneg Shabbat. The cost is $22. Reservations are due by Feb. 27. Call 215-677-1600. ••

Fox Rok holding spring signups

Fox Rok is holding baseball and softball registrations for boys ages 4 to 17 and girls ages 4-18. Registrations will be held until Feb. 28, but divisions will close once the maximum number of players have registered. For cost, additional details or to register, visit www.foxrokaa.com. ••

Sports Hall of Fame banquet at FOP

The City All Star Chapter Pennsylvania Sports Hall of Fame will hold its 29th awards banquet on Tuesday, April 18, at 5:30 p.m. at Fraternal Order of Police Lodge 5, 11630 Caroline Road.

The class of 2023 consists of former North Catholic soccer coach Jerry Brindisi; former Northeast High football coach Harvey “Brew” Schumer; Frank “Roscoe” Natale, who has coached baseball and been athletic director at Southern and Bok and been football coach at Bok, Bartram and Southern; and former La Salle University and Archbishop Ryan baseball coach Mike Lake.

In addition, the class of 2020 will be recognized. The banquet honoring them was postponed due to COVID.

Those inductees are former La Salle University basketball player Craig Conlin; coach and youth league organizer Lou DeCree; retired longtime women’s college basketball official Dennis DeMayo; Division I football official Joe Griesser; Joe Hand, a leading TV distributor of closed-circuit and pay-per-view boxing; Mike Hawkins, the PIAA District 12 chairman and former football coach and athletic director at Germantown High School; Steve Kane, the longtime former boys basketball coach at University City who led the Jaguars to the 1995 Public League title; Mike Koplove, who pitched for the Arizona Diamondbacks and Cleveland Indians; Kathy Lonergan, a Division I women’s basketball referee; Dave Mastropietro, a baseball star at La Salle University; and Dr. Anthony Salem, a former minor league baseball player.

Tickets cost $75 in advance and $80 at the door. Tables of 10 cost $750.

Checks can be made payable to Philadelphia City All Star Chapter, and mailed to PAHOF, P.O. Box 672, Levittown, PA 19055-9998 (include email address and inductee name on check). No paper tickets will be issued. Instead, guests will go to a welcome table at the FOP to get their seat assignments.

Organizers are also looking for sponsors for an ad book.

For tickets or ads, contact Steve DiSangro at disangroref@aol.com or 215-421-7556. ••

NE native wins engineering award

The Engineers’ Club of Philadelphia announced that Archibald S. Filshill, Ph.D., a Northeast native, George Washington High School graduate and founder and CEO of Aero Aggregates of North America, has been elected as the 2023 Delaware Valley Engineer of the Year.

“The Engineers’ Club of Philadelphia is honored to have Archie represent the Delaware Valley as the 2023 Engineer of the Year,” said Bob Wright, chairman of the Delaware Valley Engineers Week Committee. “Archie has used his years of engineering experience and knowledge from his academic studies as a foundation to excel in his entrepreneurial ventures, where he continues to transform the industry for engineers.” ••

Purim service

Congregations of Shaare Shamayim, 9768 Verree Road, will be holding its Purim services and reading of the Megillah on Monday, March 6. The evening starts at 6 p.m. with a light dinner, followed by a 7 p.m. Ma’ariv service and Megillah reading. Call 215-677-1600 to RSVP. ••

Job fair at PATH

People Acting to Help will be hosting a job fair with walk-in interviews at its headquarters at 1919 Cottman Ave. (at Castor Avenues), on Wednesday, March 8, from 2 to 6 p.m. PATH is hiring for positions in both its behavioral health and intellectual disability programs, from entry-level residential to credentialed clinical and program staff as well as administrative positions. Potential staff should bring their resumes. Free parking is available in the PATH lot. To learn more about PATH and see its available positions, visit www.pathcenter.org. ••

Balloon Show at Holmesburg Library

Holmesburg Library, 7810 Frankford Ave., will host a Balloon Show on Wednesday, March 8, at 6 p.m. The public is invited for a fun show with lots of audience participation. Balloon shapes will be used to help kids act out a story and create a show. ••

Benefit for autism

Somerton’s Top Hat Dance Studio will hold Come Dance with Our Stars on Sunday, March 26, from noon to 4 p.m. at Spring Mill Country Manor, 171 Jacksonville Road, Ivyland. The luncheon costs $40. There will be prizes, raffles and a 50/50. Proceeds benefit Rydal’s Center at Hampton House, which offers services to people with autism and intellectual disabilities. Call 215-885-3971. ••

North communion breakfast

The Northeast Catholic Alumni Communion Breakfast will take place on April 16 at Cannstatter’s, 9130 Academy Road. Register at www.northcatholicalumni.org. ••

All-star games at Holy Family

The Philadelphia Building & Construction Trades Council announced that the Philadelphia All Star Labor Classic basketball game will be played Sunday, April 16, at Holy Family University, 9801 Frankford Ave. Proceeds will benefit the Greater Delaware Valley Chapter of the National Multiple Sclerosis Society. The event pits the City Boys vs. Suburban Boys at 2:45 p.m. and the City Girls vs. Suburban Girls teams at 1:15. Every participating player receives a $500 college scholarship, thanks to sponsorships. Prior to the two main events, attendees can enjoy the Labor All Stars vs. Media All Stars at noon. Admission is free. To learn more about sponsorship opportunities, email laborclassic@gmail.com. ••

Mayoral debate at Holy Family

The Greater Northeast Philadelphia Chamber of Commerce will sponsor a mayoral debate on Tuesday, April 18, in the gym at Holy Family University, located in the Campus Center, close to the entrance at Frankford Avenue and Stevenson Lane. Doors open at 6 p.m. The debate begins at 7. The moderators will be Dan McElhatton, a lawyer, former city councilman and chair of the GNPCC’s government affairs committee; Northeast Times editor Tom Waring; and Jennifer Lewis-Hall, of PHL17. A Holy Family student will have the chance to ask a couple of questions. The public is invited. ••

Celebrating 100 years of SMT

St. Martin of Tours Parish invites all school alumni, current and past parishioners and friends to a 100th anniversary Mass in the upper church, 5450 Roosevelt Blvd., on Sunday, April 30, at noon. The Mass will be celebrated by Archbishop Edward Adams. Afterward, there will be a “Past & Present — Building Our Future” celebration at Cannstatter’s, 9130 Academy Road, from 2-6 p.m. Tickets cost $35 and include food, soft drinks, music and door prizes. The event is for ages 21-plus. Tickets must be purchased in advance in the rectory, after all Masses, through Venmo (@smotphilly) or with check to St. Martin of Tours Church, 5450 Roosevelt Blvd., Philadelphia, PA 19124, Attn: Centennial Celebration. Proceeds will benefit church improvements. ••

Train show in March

The Train Collectors Association Atlantic Division will hold its Spring Fever Train Show and Sale on Sunday, March 5, from 9 a.m. to 1 p.m. at Penns Landing Caterers (Sheet Metal Workers Union Hall), 1301 S. Columbus Blvd. There will be 140 tables with a variety of vintage toy trains and repair parts for sale, test track, operating toy train layouts, kids activities and door prizes for adults and children. Admission is $5 per attendee or per family of two adults and all children 12 and under. Food is available on premises, and there is plenty of free parking. For more information, visit www.ADTCA.com or call Bob at 610-872-3309. ••

Red Cross blood drive

Congregations of Shaare Shamayim, 9768 Verree Road, is holding a blood drive being run by the American Red Cross on Sunday, March 19, from 8:30 a.m. to 1:30 p.m. Volunteers are needed to check people in and assist where needed. Light refreshments will be served. To reserve your time slot or for more details, call the CSS office at 215-677-1600. ••

Tae Kwon Do competition

Red Tiger Tae Kwon Do will hold its USTC Red Tiger Cup on Saturday, May 6, at 8 a.m. at Bucks County Community College, 275 Swamp Road in Newtown. Students will compete in sparring, patterns and special technique with trophies and medals awarded to the top three competitors in each division. Call 215-969-9962. ••

Book club’s March meeting set

The Book Club of Congregations of Shaare Shamayim will be holding a Zoom session on Monday, March 6, at 7 p.m. The book is The Exiles by Christina Baker Kline. For further information, or to register for the book club program, call Lynn Ratmansky at the synagogue office at 215-677-1600. ••

Celebrate 60 years

Congregations of Shaare Shamayim, 9768 Verree Road, invites the public to celebrate 60 years of memories and moments on Sunday, March 26, at noon. There will be a brunch buffet, dessert station, mimosas, videos and personal recollections. The cost is $25. Checks payable to Congregations of Shaare Shamayim can be sent to 9768 Verree Road, Philadelphia, PA 19115. The deadline is March 13. Call 215-677-1600. ••

Sisterhood meeting in March

The Sisterhood of Congregations of Shaare Shamayim, 9768 Verree Road, will meet on Tuesday, March 14, at 1 p.m. The speaker will be Rabbi Sandi Berliner. Her topic will be: “What’s on your seder plate – Updating your Seder.” Light refreshments will be served. Admission is free. Call 215-677-1600. ••

Trip to American Dream

St. Leo’s Knights of Columbus 1294 in Tacony is running a bus trip to the American Dream retail and entertainment complex in East Rutherford, New Jersey on Saturday, March 25. The bus will depart at 9:15 a.m. at St. Hubert High School, Cottman Avenue and Ditman Street, and will leave American Dream at 6 p.m. The price of the trip is $47 per person (bus driver gratuity included). Anyone interested in attending the trip can contact John McKenna at 267-242-3975 or johnmmckenna@comcast.net. ••

Trip to Mackinac Island, Michigan

The Polish American Cultural Center Museum volunteers are sponsoring a 7-day, 6-night trip to Mackinac Island, Michigan from July 9-15. The trip consists of a ferry ride to Mackinac Island, two nights at the Grand Hotel, a horse-drawn carriage ride and visits to Bronner’s Christmas Wonderland, the Henry Ford Museum and the National Shrine of the Cross in the Woods. The price includes bus transportation, hotels, six breakfasts, six dinners, a buffet luncheon at the Grand Hotel, admission to all attractions, baggage handling, taxes and gratuities. Call Theresa Romanowski at 215-813-2780 or 215-922-1700. ••

Book review and dinner at Maggio’s

The Marlyn Chakov Fein Chapter, Fox Chase Cancer Center is having a book review on Wednesday, March 15, at Maggio’s Restaurant, 400 2nd Street Pike, Southampton, at 6 p.m. The book being discussed is Yellow Wife, by Sadeqa Johnson. The cost is $40, which includes dinner and dessert. Call Joyce at 267-808-2022 for reservations. The event supports cancer research and compassionate patient care at Fox Chase Cancer Center. ••

Magic show and dinner

The Marlyn Chakov Fein Chapter, Fox Chase Cancer Center is hosting a magic show and dinner (adults only) on Sunday, April 2, at 3 p.m. at the Smoke & Mirrors Magic Theater, 2840 Pine Road (Landmark Business Center), Huntingdon Valley. Doors open at 2:40 p.m. The cost is $55 per person and includes show and food from Ben & Irv’s restaurant. Call Bernadette at 570-401-8417 for information and tickets. The event supports cancer research and compassionate patient care at Fox Chase Cancer Center. ••

Book club to meet in April

The Book Club of Congregations of Shaare Shamayim will be holding a Zoom session on Monday, April 3, at 7 p.m. The book is The Masterpiece by Fionna Davis. For further information, or to register for the book club program, call Lynn Ratmansky at the synagogue office at 215-677-1600. ••

Afternoon Tea in Bristol

The Marlyn Chakov Fein Chapter, Fox Chase Cancer Center is hosting a traditional Afternoon Tea on Saturday, April 15, at noon at Bricky Girl Tea Room, 236 Mill St., Bristol. There will be contests for Best Fancy Hat, Best Funny Hat and Best High Tea Look. For tickets, call Lauren at 267-304-6396. The event supports cancer research and compassionate patient care at Fox Chase Cancer Center. ••

Casino trip to Atlantic City

The Marlyn Chakov Fein Chapter, Fox Chase Cancer Center is running a casino trip to Caesars Atlantic City on Tuesday, April 18. The cost is $40 and includes round-trip motor coach and $20 in slot dollars. Bus will leave from 604 Township Line Road, Cheltenham, at 9:45 a.m. and return about 8 p.m. Call Elaine at 215-913-9237 for reservations. This event supports cancer research and compassionate patient care at Fox Chase Cancer Center. ••

Music, refreshments at meeting

The Sisterhood of Congregations of Shaare Shamayim, 9768 Verree Road, will host a meeting on Tuesday, April 18, at 7 p.m. Cantor Don Samuels will entertain the crowd with a vocal medley, accompanied by pianist Josh Yudkin. Light refreshments will be served. Admission is free. Call 215-677-1600. ••

Entertainer Primerano on stage

Singer/pianist John Primerano will appear at Sellersville Theater, 24 W. Temple Ave. in Sellersville, on April 22, at 8 p.m. For tickets, call 215-257-5808. For more information, visit JohnPrimerano.com. ••

Sisterhood meeting in May

The Sisterhood of Congregations of Shaare Shamayim, 9768 Verree Road, will be hosting a meeting on Tuesday, May 16. Doors open at 7 p.m., with the program beginning at 7:30. Lynn Levin will speak about her new collection of short stories entitled House Parties. Levin is a poet, author, translator and adjunct associate professor in the Department of English and Philosophy at Drexel University. Copies of her book will be available for sale for $20. Light refreshments will be served. There is no charge for the program. Call the synagogue office at 215-677-1600. ••

Cultural trip to Bryn Athyn Cathedral

The Sisterhood of Congregations of Shaare Shamayim will take a one-hour tour of Bryn Athyn Cathedral on Thursday, May 18, at 1 p.m. There are no steps, and restrooms are accessible. The cost is $10 per person. To register, send a check, payable to CSS Sisterhood, with Bryn Athyn on the memo line, to the CSS office, 9768 Verree Road, Philadelphia, PA 19115, Attn: Bryn Athyn. Include the name, email address and phone number of each person registering. For questions, call Lynn Azoulay at 215-677-1600. ••

VFW looking for members

Bustleton-Somerton/CTR1 Michael J. Strange VFW Post 6617 meets on the third Wednesday of every month at American Legion Post 810, 9151 Old Newtown Road. Meetings start at 7:30 p.m. If you are a military veteran who served in a designated combat zone, you are eligible to join the VFW. Contact Commander Israel Wolmark at 215-725-0630 if you would like to join the post. ••

Go see Mamma Mia!

The Star Players, of the city Department of Parks and Recreation, will present Mamma Mia! from June 2-4 at 7 p.m. at Venice Island Performing Arts Center, 7 Lock St. in Manayunk. Tickets cost $15 in advance and $20 at the door. Group rates are available. Tickets are available at Holmesburg Recreation Center, 4500 Rhawn St., or on Venmo @TheStarplayers. For more information, contact director Bill Arthur at 215-685-8714 or Starplayers2013@gmail.com. ••

FCCC researcher earns grant

John Karanicolas, co-leader of the Cancer Signaling and Microenvironment research program at Fox Chase Cancer Center, was recently awarded a $1 million grant from the W.M. Keck Foundation to develop a platform that could assist in the development of new drugs.

“Scientifically, the goal of this project is to design new compounds known as molecular glues,” Karanicolas said.

Molecular glues are small molecules that bind to the surface of a target protein and change its shape, allowing it to engage with a different set of protein partners than its usual repertoire.

“This is important because in many cases proteins act on their signaling partners through proximity, so simply bringing two proteins close to one another can, in some special cases, be enough to activate the signaling pathway,” Karanicolas said. “This idea of molecular glues can be used to enhance existing signaling pathways or to rewire cellular signaling pathways in a way that may allow us to reach what were previously ‘undruggable’ targets,” meaning ones that do not respond to existing drugs.

Karanicolas’ project, “Using Deep Learning to Enable Rational Design of Molecular Glues,” aims to develop machine learning tools for identifying compounds that stabilize select protein interactions. Machine learning is a process by which computers are taught how to learn and perform certain functions. He and a team of five other Fox Chase investigators will then test in cancer cells whether the compounds designed on the computer induce association of the selected target proteins.

He added that, if successful, the studies will provide a necessary shift away from techniques that simply hope to find molecular glues by serendipity and move instead toward rational design methods that will enable much broader applications.

“What’s tremendous about the Keck Foundation is that they’re funding the project in a very holistic way because of their forward-thinking focus. The grant mechanism is unique in that it’s really supporting the overarching conceptual goal of the project and allows us to defer for later the specific applications,” Karanicolas said. “I’m very excited that this grant is supporting us in doing these truly cutting-edge fundamental studies, since these will open the door to countless new applications.” ••

Upcoming cruise

The Bristol Cultural and Historical Foundation is sponsoring a fully escorted Holy Lands & Aegean Majesty cruise from Oct. 6-17, visiting Israel, Cyprus, Greece, Turkey and Italy. Rates, including airfare, range from $4,298 to $8,098 per person, double occupancy. Call 215-788-9408 for information and reservations. ••

Cruise the Mediterranean

Norwegian Cruise Line will host a Mediterranean cruise from Rome to Venice on Oct. 10-19. The trip is all inclusive with round-trip airfare, a beverage package, all meals, three specialty dinners, taxes, transfers and all gratuities. The cost for a balcony sea view cabin is $3,511 per person. For more information, contact Fillmore Travel’s Kevin Fries at 215-498-8294 or fkevin910@comcast.net. ••

South Phila. HS class of ‘68 reunion

The South Philadelphia High School Class of 1968 will hold its 55th reunion on Saturday, Oct. 21, from noon to 4 p.m. at the Waterfall Room, 2015 S. Water St. Tickets cost $60 and include buffet dinner and open bar. For tickets and more information, call Arleen Liberi [609-922-2419], Maria Leati [856-287-3734] or Stephen Michielli [267-252-2740]. ••

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